Endocrine Abstracts

Background: Hypokalemic Thyrotoxic Periodic Paralysis (HTPP) is a rare acquired muscular channelopathy that develops in the context of thyrotoxicosis. It consists of episodes of painless muscle weakness, precipitated by exercise, fasting, or high-carbohydrate meals. Men among ages 20-40 are more frequently affected than woman. Thyrotoxicosis (and its subsequent beta-adrenergic stimulation) increases the activation of the Sodium-Potassium ATPase channels, which leads to hyperpo...

Background: Thyroid nodules are one of the most common clinical entities in Endocrinology practice. Fine needle aspiration (FNA) and the 2017 Bethesda System for Reporting Thyroid Cytopathology have been proved to be an effective tool to identify malignancy risk and guide surgical decision-making. However, thyroid nodules classified as Bethesda (BTH) III and IV remain a challenge, considering the varying risk of malignancy (ROM) found in different papers. The aim of this study...

Background: Thionamides are a class of drugs used to control thyrotoxicosis. A wide range of systemic adverse effects have been described, including agranulocytosis, rash, fever, arthralgia, hepatitis and even drug-induced lupus. Besides, there are some uncommon events related to their use, such as pleural effusion (only eight cases have been previously reported). We report a case of methimazole-induced eosinophilic pleural effusion.Case: Our patient is ...

Introduction: PRES it’s a neurologic syndrome with multiple manifestations, that includes high blood pressure with a variable range. It usually develops in the context of medications or an underlying condition. The treatment is usually symptomatic and determined by said disease.Objective: We present the case of a patient with PRES linked to the diagnostic of a metastatic PHEO.Case-report: A 72-year-old male underwent left adre...